Article
Cell transformation disrupts the efficiency of chromosome segregation through microtubule detyrosination
2018-01-12
Abstract excerpt
The general principles of chromosome segregation are highly conserved throughout eukaryotic evolution. However, it is unknown whether there are differences in spindle or kinetochore composition or architecture which influence the efficiency chromosome segregation in different cell types. Here we show that the transition of human retinal pigment epithelial cells to a mesenchymal phenotype causes a stabilisation of...
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Identifiers and source
- Literature Corpus work
- a3b5c7da-342f-5c90-9a10-8dfd7a93c964
- DOI
- 10.1101/246983