Article

Non-Random Mis-Segregation of Human Chromosomes

2018-03-08

Abstract excerpt

<h4>Summary</h4> Recurrent patterns of chromosomal changes (aneuploidy) are widespread in cancer. These patterns are mainly attributed to selection processes due to an assumption that human chromosomes carry equal chance of being mis-segregated into daughter cells when fidelity of cell division is compromised. Human chromosomes vary widely in size, gene density and other parameters that might generate bias in mis...

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Literature Corpus work: 869692ab-f12b-5667-83c6-8a10de350383
DOI: 10.1101/278697

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