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Article

Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.

PloS one - 1 Jan 2011

Kong Xiangduo, Stephens Jared, Ball Alexander R, Heale Jason T, Newkirk Daniel A, Berns Michael W, Yokomori Kyoko

Abstract excerpt

Condensin I is important for chromosome organization and segregation in mitosis. We previously showed that condensin I also interacts with PARP1 in response to DNA damage and plays a role in single-strand break repair. However, whether condensin I physically associates with DNA damage sites and how PARP1 may contribute to this process were unclear. We found that condensin I is preferentially recruited to DNA...

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Source

Open in PubMed Open full text

Identifiers

PMID: 21858164
DOI: 10.1371/journal.pone.0023548
PMCID: PMC3155556

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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