Article

Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression

2020-05-07

Abstract excerpt

<title>Abstract</title> <p>Genetic and epigenetic factors contribute to the development of the spinal cord. Failure in correct exertion of the developmental programs, including neurulation, neural tube closure and neurogenesis of the diverse spinal cord neuronal subtypes results in clinical phenotypes with variable severity. The histone methyltransferase Disruptor of Telomeric 1 Like (DOT1L), which mediates histo...

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Literature Corpus work: a2fea384-cfd1-5b5b-b571-fa933468e881
DOI: 10.21203/rs.2.23363/v2

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