Article
Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1.
Neuron - 1 Feb 2001
Pierani A, Moran-Rivard L, Sunshine M J, Littman D R, Goulding M, Jessell T M
Abstract excerpt
Spinal interneurons help to coordinate motor behavior. During spinal cord development, distinct classes of interneurons are generated from progenitor cells located at different positions within the ventral neural tube. V0 and V1 interneurons derive from adjacent progenitor domains that are distinguished by expression of the homeodomain proteins Dbx1 and Dbx2. The spatially restricted expression of Dbx1 has a...
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