Article

Association of DOT1L histone methyltransferase with non-syndromic orofacial clefts in a cohort of children of African and Asian ancestry

2026-06-29

Abstract excerpt

Non-syndromic orofacial clefts (nsOFCs), such as cleft lip, cleft lip with or without cleft palate (CL/P), and cleft palate only, are among the most common craniofacial malformations in humans. We identified a range of rare and de novo structural variants (SVs) associated with nsOFCs in a cohort of children of African and Asian ancestry from the Gabriella Miller Kids First Data Resource Center. Most of these nove...

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Literature Corpus work: 29a48dca-2fba-5a59-9b7c-185843ccd025
DOI: 10.64898/2026.06.26.26356682

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