Article

Parallelized engineering of mutational models using piggyBac transposon delivery of CRISPR libraries

2020-07-11

Abstract excerpt

Novel gene and variant discoveries have reached unprecedented scale with the emergence of exome and genome sequencing studies across a spectrum of human disease initiatives. Highly parallelized functional characterization of these variants is now paramount to deciphering disease mechanisms, and approaches that facilitate editing of induced pluripotent stem cells (iPSCs) to derive otherwise inaccessible tissues of...

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Literature Corpus work: a2e80926-3438-584d-8cd9-5d238f46b16d
DOI: 10.1101/2020.07.10.197962

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