Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prime Editing Driven Functional Genomics: Bridging Genotype to Phenotype in the Post-Genomic Era.

International journal of molecular sciences - 10 Feb 2026

Begum Syeda N, Hasan Syed K

Abstract excerpt

The post-genomic era, defined by large-scale sequencing initiatives, has generated an unprecedented catalogue of human genetic variation. Yet, the vast majority of genetic variants remain classified as variants of uncertain significance or are located within poorly characterized non-coding regions, thereby hindering the effective translation of genomic data into meaningful biological understanding and clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR-Cas Systems
Share to Gene Editing
Share to Genomics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 41751840
DOI: 10.3390/ijms27041703
PMCID: PMC12940846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prime Editing Driven Functional Genomics: Bridging Genotype to Phenotype in the Post-Genomic Era.PMID 41751840Read ↗

Analyzing the functional effects of DNA variants with gene editing.Semantic proximity Read ↗

Base Editing and Prime Editing: Potential Therapeutic Options for Rare and Common Diseases.Semantic proximity Read ↗

Recent advances in CRISPR-based functional genomics for the study of disease-associated genetic variants.Semantic proximity Read ↗

Saturation variant interpretation using CRISPR prime editingSemantic proximity Read ↗

Building Gene Editing Platforms for Personalized Medicine: The Next Step in Interventional GeneticsSemantic proximity Read ↗

Saturation variant interpretation using CRISPR prime editing.Semantic proximity Read ↗

DNA Prime Editing: A New CRISPR-Based Method to Correct Most Disease-Causing Mutations.Semantic proximity Read ↗

Atlas of CRISPR Correction of Pathogenic Human Genetic VariantsSemantic proximity Read ↗

Decoding disease-relevant variants with base and prime editors at scale.Semantic proximity Read ↗

Prime editing: A gene precision editing tool from inception to present.Semantic proximity Read ↗

Automated design of CRISPR prime editors for thousands of human pathogenic variantsSemantic proximity Read ↗

A new era in functional genomics screens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.