Article

The Role of Proton Transport in Gating Current in a Voltage Gated Ion Channel, as Shown by Quantum Calculations

2018-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Over two-thirds of a century ago, Hodgkin and Huxley proposed the existence of voltage gated ion channels (VGIC) to carry Na + and K + ions across the cell membrane to create the nerve impulse, in response to depolarization of the membrane. The channels have multiple physiological roles, and play a central role in a wide variety of diseases when they malfunction. The first channel structure wa...

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Literature Corpus work: a2d7edc7-53ba-5435-adbe-183c6c859ff4
DOI: 10.1101/371914

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