Article

The role of the mutT gene of Escherichia coli in maintaining replication fidelity

1997-08-01

Abstract excerpt

Spontaneous mutation levels are kept low in most organisms by a variety of error-reducing mechanisms, some of which ensure a high level of fidelity during DNA replication. The mutT gene of Escherichia coli is an important participant in avoiding such replication mistakes. An inactive mutT allele is a strong mutator with strict mutational specificity: only A·T→C·G transversions are enhanced. The biological role of...

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Literature Corpus work: a2c69fe3-9084-5d16-934d-7892619bdb6e
DOI: 10.1016/s0168-6445(97)00045-4

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