Article
The microbiology of mutability.
FEMS microbiology letters - 1 Dec 2007
Sundin George W, Weigand Michael R
Abstract excerpt
Bacteria possessing elevated spontaneous mutation rates are prevalent in certain environments, which is a paradox because most mutations are deleterious. For example, cells with defects in the methyl-directed mismatch repair (MMR) system, termed mutators or hypermutators, are overrepresented in populations of bacterial pathogens, with the mutator trait hypothesized to be advantageous in the changing host...
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