Article
DNA methylation and mutator genes in Escherichia coli K-12.
Mutation research - 1 Oct 2010
Marinus Martin G
Abstract excerpt
Mutator strains of Escherichia coli have been used to define mechanisms that account for the high fidelity of chromosome duplication and chromosome stability. Mutant strains defective in post-replicative mismatch repair display a strong mutator phenotype consistent with a role for correction of mismatches arising from replication errors. Inactivation of the gene (dam) encoding DNA adenine methyltransferase...
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