Article
Microglia-specific promoter activities of human <i>HexB</i> gene
2021-10-28
Abstract excerpt
Adeno-associated virus (AAV)-mediated genetic targeting of microglia remains challenging. Overcoming this hurdle is essential for gene editing in the central nervous system (CNS). Here, we characterized the minimal/native promoter of the HexB gene, which is known to be specifically and stably expressed in the microglia during homeostatic and pathological conditions. Dual reporter and serial deletion assays identi...
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Identifiers and source
- Literature Corpus work
- a24d5b47-31a9-5786-a43d-e86699ee9499
- DOI
- 10.1101/2021.10.28.465974