Article

Development of an AAV Vector System for Highly Specific and Efficient Gene Expression in Microglia

2024-11-06

Abstract excerpt

Microglia play a critical role in diseases such as Alzheimer’s and stroke, making them a significant target for therapeutic intervention. However, due to their immune functions in detecting and combating viral invasion, efficient gene delivery to microglia remains challenging. We achieved specific and efficient gene delivery to microglia using an adeno- associated virus (AAV) vector designed for this purpose. This...

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Literature Corpus work: 3df8fc07-afaf-5e52-a478-fc1e73d1c0f6
DOI: 10.1101/2024.11.05.622037

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