Article
Highly Efficient Lentiviral Transduction of Human iPSC-Derived Microglia and Macrophages
2026-05-27
Abstract excerpt
<h4>Background</h4> Microglia have become a cell type of interest in the neurodegenerative field given both genetic and pathological evidence for their role in disease development and progression. There has been a rapid growth of studies using iPSC-derived microglial models to understand the molecular mechanisms driving these neurological diseases. However, it remains difficult to transduce myeloid cells effectiv...
Topics
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- Cytomegalovirus and herpesvirus research
- HIV Research and Treatment
- Mosquito-borne diseases and control
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA Interference and Gene Delivery
- Viral Infections and Immunology Research
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- 3c6b40ab-68ce-52d1-8a5a-17ea13a27667
- DOI
- 10.64898/2026.05.23.727402