Article

Molecular Characterization of the Men1 Tumor Suppressor Gene in Sporadic Pituitary Tumors

1998-04-01

Abstract excerpt

Anterior pituitary tumors arise sporadically, and also as part of the inherited multiple endocrine neoplasia type 1 (MEN 1) syndrome. To investigate the role of the recently isolated men1 gene in sporadic pituitary tumorigenesis, the complete coding sequence was screened for mutations in 45 sporadic anterior pituitary tumors, including 14 hormone-secreting tumors and 31 nonsecreting tumors, by dideoxy fingerprinti...

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Literature Corpus work: a1089045-a948-564d-9d1e-35893cfa25f2
DOI: 10.1210/jc.83.4.1388

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