Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of the MEN1 gene in sporadic parathyroid tumors.

The Journal of clinical endocrinology and metabolism - 1 Aug 1998

Farnebo F, Teh B T, Kytölä S, Svensson A, Phelan C, Sandelin K, Thompson N W, Höög A, Weber G, Farnebo L O, Larsson C

Abstract excerpt

Primary hyperparathyroidism is a common endocrine disease that also occurs in a number of inherited disorders, including multiple endocrine neoplasia type 1 (MEN1). Loss of heterozygosity (LOH) in the MEN1 region on chromosome 11q13 has been found in 30% of sporadic parathyroid tumors, making the recently cloned MEN1 gene a prime candidate for involvement in parathyroid tumorigenesis. Using LOH and single strand...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Autoradiography

Share to Chromosomes, Human, Pair 11

Share to In Situ Hybridization

Share to Mutation

Share to Polymorphism, Single-Stranded Conformational

Share to RNA, Messenger

Source

Identifiers

PMID: 9709922
DOI: 10.1210/jcem.83.8.4846

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of the MEN1 gene in sporadic parathyroid tumors.PMID 9709922Read ↗

MEN1 gene alterations do not correlate with the phenotype of sporadic primary hyperparathyroidism.Semantic proximity Read ↗

Somatic mutation of the MEN1 gene in parathyroid tumours.Semantic proximity Read ↗

Analysis of the MEN1 gene in sporadic pituitary adenomas.Semantic proximity Read ↗

Screening of the Men1 gene and discovery of germ-line and somatic mutations in apparently sporadic parathyroid tumors.Semantic proximity Read ↗

Loss of heterozygosity in sporadic parathyroid tumours: involvement of chromosome 1 and the MEN1 gene locus in 11q13.Semantic proximity Read ↗

Six novel MEN1 gene mutations in sporadic parathyroid tumors.Semantic proximity Read ↗

MEN1 gene analysis in sporadic adrenocortical neoplasms.Semantic proximity Read ↗

Parathyroid MEN1 gene mutations in relation to clinical characteristics of nonfamilial primary hyperparathyroidism.Semantic proximity Read ↗

Somatic mutations of multiple endocrine neoplasia type 1 gene in the sporadic endocrine tumors.Semantic proximity Read ↗

Screening for MEN1 tumor suppressor gene mutations in sporadic pituitary tumors.Semantic proximity Read ↗

Multiple endocrine neoplasia type 1 (MEN1): LOH studies in a affected family and in sporadic cases.Semantic proximity Read ↗

Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.