Article
11q13 allelic loss in pituitary tumors in patients with multiple endocrine neoplasia syndrome type 1.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 1998
Weil R J, Vortmeyer A O, Huang S, Boni R, Lubensky I A, Pack S, Marx S J, Zhuang Z, Oldfield E H
Abstract excerpt
Pituitary adenomas may develop sporadically or as part of the multiple endocrine neoplasia type 1 (MEN 1) syndrome. The gene responsible for MEN 1 syndrome was recently identified and cloned. Low rates of MEN 1 gene mutations and deletions have been reported in sporadic pituitary adenomas. To elucidate the role of the MEN 1 gene in the pathogenesis of MEN 1-associated pituitary tumors, we examined pituitary...
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