Article
11q13 allelic loss in pituitary tumors in patients with multiple endocrine neoplasia syndrome type 1.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 1998
Weil R J, Vortmeyer A O, Huang S, Boni R, Lubensky I A, Pack S, Marx S J, Zhuang Z, Oldfield E H
Abstract excerpt
Pituitary adenomas may develop sporadically or as part of the multiple endocrine neoplasia type 1 (MEN 1) syndrome. The gene responsible for MEN 1 syndrome was recently identified and cloned. Low rates of MEN 1 gene mutations and deletions have been reported in sporadic pituitary adenomas. To elu...
Topics
- Adenoma
- Adult
- Aged
- Alleles
- Child, Preschool
- Female
- Gene Deletion
- Humans
- Loss of Heterozygosity
- Male
- Middle Aged
- Multiple Endocrine Neoplasia Type 1
