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Article

Mutations of the MEN1 tumor suppressor gene in sporadic pituitary tumors.

Cancer letters - 19 Jul 1999

Wenbin C, Asai A, Teramoto A, Sanno N, Kirino T

Abstract excerpt

Pituitary adenoma is a common neoplasm accounting for 10% of all intracranial tumors. Although the molecular mechanisms underlying the formation of these tumors are largely unknown, a small portion of pituitary adenomas occur in patients with the multiple endocrine neoplasia syndrome type 1 (MEN 1). Although two groups in the United States and Canada have recently reported that sporadic pituitary adenomas very...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10424779
DOI: 10.1016/s0304-3835(99)00111-1

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Mutations of the MEN1 tumor suppressor gene in sporadic pituitary tumors.PMID 10424779Read ↗

Mutations of the MEN1 tumor suppressor gene in pituitary tumors.Semantic proximity Read ↗

Molecular Characterization of the Men1 Tumor Suppressor Gene in Sporadic Pituitary TumorsSemantic proximity Read ↗

Molecular characterization of the men1 tumor suppressor gene in sporadic pituitary tumors.Semantic proximity Read ↗

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Analysis of the MEN1 gene in sporadic pituitary adenomas.Semantic proximity Read ↗

Somatic MEN1 gene mutation does not contribute significantly to sporadic pituitary tumorigenesis.Semantic proximity Read ↗

Clinical features of multiple endocrine neoplasia type 1 (MEN1) phenocopy without germline MEN1 gene mutations: analysis of 20 Japanese sporadic cases with MEN1.Semantic proximity Read ↗

A novel germline mutation of multiple endocrine neoplasia type 1 (MEN1) gene in a Japanese MEN1 patient and her daughter.Semantic proximity Read ↗

Genetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenoma.Semantic proximity Read ↗

Lack of mutations of exon 2 of the MEN1 gene in endocrine and nonendocrine sporadic tumors.Semantic proximity Read ↗

Multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas in Japan.Semantic proximity Read ↗

Absence of Germ-Line Mutations of the Multiple Endocrine Neoplasia Type 1 (MEN1) Gene in Familial Pituitary Adenoma in Contrast to MEN1 in Japanese1Semantic proximity Read ↗

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