Article

Exploring the Molecular Underpinnings of Cancer-Causing Oncohistone Mutants Using Yeast as a Model

2023-10-09

Abstract excerpt

Understanding the molecular basis of cancer initiation and progression is critical to develop effective treatment strategies. Recently, mutations in genes encoding histone proteins have been identified that drive oncogenesis, converting these essential proteins into “oncohistones”. Understanding how oncohistone mutations, which are commonly missense mutations, subvert the normal function of histones to drive oncog...

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Literature Corpus work: 9dbf953e-5c61-543b-b069-6cf15a935080
DOI: 10.20944/preprints202310.0398.v1

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