Article

Predicting Nicotine Metabolism Across Ancestries Using Genotypes

2021-12-19

Abstract excerpt

<h4>Background</h4> There is a need to match characteristics of tobacco users with cessation treatments and risks of tobacco attributable diseases such as lung cancer. The rate in which the body metabolizes nicotine has proven an important predictor of these outcomes. Nicotine metabolism is primarily catalyzed by the enzyme cytochrone P450 (CYP2A6) and CYP2A6 activity can be measured as the ratio of two nicotine m...

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Literature Corpus work: 9cce927b-6b4f-549d-8961-48636682472e
DOI: 10.1101/2021.12.19.21267947

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