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Article

Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Sept 2016

Baurley James W, Edlund Christopher K, Pardamean Carissa I, Conti David V, Krasnow Ruth, Javitz Harold S, Hops Hyman, Swan Gary E, Benowitz Neal L, Bergen Andrew W

Abstract excerpt

INTRODUCTION: Metabolic enzyme variation and other patient and environmental characteristics influence smoking behaviors, treatment success, and risk of related disease. Population-specific variation in metabolic genes contributes to challenges in developing and optimizing pharmacogenetic interventions. We applied a custom genome-wide genotyping array for addiction research (Smokescreen), to three...

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Identifiers

PMID: 27113016
DOI: 10.1093/ntr/ntw117
PMCID: PMC4978985

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