Article

Degradation intermediates as an indicator of mRNA and cell metabolism

2021-08-30

Abstract excerpt

Traditional mRNA degradation rate measurements involves complex experimental design with RNA labeling or transcription blocking together with sampling at multiple timepoints 1,2 . These experimental requirements limit the application of transcriptome-wide mRNA degradation rate analysis mainly in cultured cells, but rarely in in vivo samples. Therefore, a direct and simple strategy needs to be developed to study...

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Literature Corpus work: 9c536bca-3df3-5467-a294-f4f6834c26e4
DOI: 10.1101/2021.08.29.458069

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