Article

Poly(A) tail length is a major regulator of maternal gene expression during the mammalian oocyte-to-embryo transition

2021-08-31

Abstract excerpt

Transcription is silent during the mammalian oocyte-to-embryo transition (OET) until zygotic genome activation (ZGA). Therefore, the OET relies on post-transcriptional regulation of maternal mRNA, among which poly(A) tail lengths have been found to regulate translation for a small number of genes 1–3 . However, transcriptome-wide poly(A) tail length dynamics and their role in gene expression during the mammalian...

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Literature Corpus work: 092438f6-160d-530e-bebb-84f41e507c51
DOI: 10.1101/2021.08.29.458052

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