Article

The genetic and biochemical determinants of mRNA degradation rates in mammals

2022-03-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Degradation rate is a fundamental aspect of mRNA metabolism, and the factors governing it remain poorly characterized. Understanding the genetic and biochemical determinants of mRNA half-life would enable a more precise identification of variants that perturb gene expression through post-transcriptional gene regulatory mechanisms. <h4>Results</h4> Here, we establish a compe...

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Literature Corpus work: cdcb19fb-068f-5ad2-a2f5-c36f0b004b38
DOI: 10.1101/2022.03.18.484474

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