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A spatiotemporally resolved atlas of mRNA decay in the <i>C. elegans</i> embryo reveals differential regulation of mRNA stability across stages and cell types

2024-01-16

Abstract excerpt

During embryonic development, cells undergo dynamic changes in gene expression that are required for appropriate cell fate specification. Although both transcription and mRNA degradation contribute to gene expression dynamics, patterns of mRNA decay are less well-understood. Here we directly measured spatiotemporally resolved mRNA decay rates transcriptome-wide throughout C. elegans embryogenesis by transcription...

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Literature Corpus work
59e918df-fd3f-5e9c-98fa-cd9bfca179cc
DOI
10.1101/2024.01.15.575757
Open publication

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A spatiotemporally resolved atlas of mRNA decay in the <i>C. elegans</i> embryo reveals differential regulation of mRNA stability across stages and cell typesDOI 10.1101/2024.01.15.575757
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