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Article

MicroRNAs control mRNA fate by compartmentalization based on 3′ UTR length in male germ cells

12 Jun 2017

Abstract excerpt

BACKGROUND: Post-transcriptional regulation of gene expression can be achieved through the control of mRNA stability, cytoplasmic compartmentalization, 3' UTR length and translational efficacy. Spermiogenesis, a process through which haploid male germ cells differentiate into spermatozoa, represents an ideal model for studying post-transcriptional regulation in vivo because it involves a large number of...

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PMID: 28615029
DOI: 10.1186/s13059-017-1243-x

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