Article

DRUID: A pipeline for reproducible transcriptome-wide measurements of mRNA stability

2017-06-12

Abstract excerpt

<h4>SUMMARY</h4> Control of messenger RNA (mRNA) stability is an important aspect of gene regulation. The gold standard for measuring mRNA stability transcriptome-wide uses metabolic labeling, biochemical isolation of labeled RNA populations, and high-throughput sequencing. However, difficult normalization procedures and complex computational algorithms have inhibited widespread adoption of this approach. Here, w...

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Literature Corpus work: 63cccdfe-3a68-5c3b-b8d2-03fd62f6e1e0
DOI: 10.1101/149195

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