Article

Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis

2019-10-15

Abstract excerpt

<h4>Background: </h4> Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease whose pathogenesis remains incompletely understood. Increasing evidence suggests that both genetic susceptibilities and changes in DNA methylation influence pivotal biological pathways and thereby contribute to the disease. The role of DNA methylation in SSc has not been fully elucidated, because existing investigations o...

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Literature Corpus work: 9c3aa9b9-b250-5ec9-ba72-c17a8087e7aa
DOI: 10.21203/rs.2.12858/v3

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