Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential DNA Methylation Landscape in Skin Fibroblasts from African Americans with Systemic Sclerosis.

Genes - 20 Jan 2021

Baker Frost DeAnna, da Silveira Willian, Hazard E Starr, Atanelishvili Ilia, Wilson Robert C, Flume Jonathan, Day Kayleigh L, Oates James C, Bogatkevich Galina S, Feghali-Bostwick Carol, Hardiman Gary, Ramos Paula S

Abstract excerpt

The etiology and reasons underlying the ethnic disparities in systemic sclerosis (SSc) remain unknown. African Americans are disproportionally affected by SSc and yet are underrepresented in research. The aim of this study was to comprehensively investigate the association of DNA methylation levels with SSc in dermal fibroblasts from patients of African ancestry. Reduced representation bisulfite sequencing (RRBS)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Fibroblasts

Share to Gene Ontology

Share to Scleroderma, Systemic

Source

Open in PubMed Open full text

Identifiers

PMID: 33498390
DOI: 10.3390/genes12020129
PMCID: PMC7909410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential DNA Methylation Landscape in Skin Fibroblasts from African Americans with Systemic Sclerosis.PMID 33498390Read ↗

Differential DNA methylation landscape in skin fibroblasts from African Americans with systemic sclerosisSemantic proximity Read ↗

Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsetsSemantic proximity Read ↗

Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesisSemantic proximity Read ↗

Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis.Semantic proximity Read ↗

Distinct genome-wide DNA methylation and gene expression signatures in classical monocytes from African American patients with systemic sclerosisSemantic proximity Read ↗

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberranciesSemantic proximity Read ↗

Unfolding the pathogenesis of scleroderma through genomics and epigenomics.Semantic proximity Read ↗

Epigenomics and Transcriptomics of Systemic Sclerosis CD4+ T cells reveal Long Range Dysregulation of Key Inflammatory Pathways mediated by disease-associated Susceptibility LociSemantic proximity Read ↗

Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis.Semantic proximity Read ↗

Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci.Semantic proximity Read ↗

RUNX1 is Expressed in a Subpopulation of Dermal Fibroblasts and Higher RUNX1 Levels are Associated with the Severity of Systemic SclerosisSemantic proximity Read ↗

Genome-Wide DNA Methylation Analysis in Systemic Sclerosis Reveals Hypomethylation of IFN-Associated Genes in CD4+ and CD8+ T CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.