Article

Functional genomics in primary T cells and monocytes identifies mechanisms by which genetic susceptibility loci influence systemic sclerosis risk

2022-05-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Systemic sclerosis (SSc) is a complex autoimmune disease with a strong genetic component. However, most of the genes associated to the disease are still unknown because associated variants affect mostly non-coding intergenic elements of the genome. The challenge now is to use functional genomics to translate the genetic findings into a better understanding of the disease. <h4>...

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Literature Corpus work: 02c4c30d-4476-5b54-ad30-63b89796a355
DOI: 10.1101/2022.05.08.22274711

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