Article

Distinct genome-wide DNA methylation and gene expression signatures in classical monocytes from African American patients with systemic sclerosis

2022-03-18

Abstract excerpt

<h4>Background</h4> Systemic sclerosis (SSc) is a multisystem autoimmune disorder that has an unclear etiology and disproportionately affects women and African Americans. Despite this, African Americans are dramatically underrepresented in SSc research. Additionally, monocytes show heightened activation in SSc and in African Americans relative to European Americans. In this study, we sought to investigate DNA meth...

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Literature Corpus work: 950adc11-5295-5746-91ab-b80f48ab6cc2
DOI: 10.1101/2022.03.17.22272588

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