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Article

Genetic and epigenetic abnormalities in systemic sclerosis.

The Journal of dermatology - 1 Jan 2016

Makino Takamitsu, Jinnin Masatoshi

Abstract excerpt

Systemic sclerosis (SSc) is a complicated autoimmune and connective tissue disease, of which the pathogenesis and treatment have not been fully elucidated. SSc patients may have a genetic predisposition, such as specific human leukocyte antigens and single nucleotide polymorphisms, but can also develop various clinical symptoms with individual differences. Epigenetics, such as DNA methylation, histone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26782002
DOI: 10.1111/1346-8138.13221

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