Article
Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets
4 Apr 2019
Abstract excerpt
BACKGROUND: Systemic sclerosis (SSc) is a rare autoimmune fibrosing disease with an incompletely understood genetic and non-genetic etiology. Defining its etiology is important to allow the development of effective predictive, preventative, and therapeutic strategies. We conducted this epigenomic study to investigate the contributions of DNA methylation to the etiology of SSc while minimizing confounding due to...
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