Article

Shared Nucleotide Flanks Confer Transcriptional Competency to bZip Core Motifs

2018-02-08

Abstract excerpt

<h4>ABSTRACT</h4> Sequence-specific DNA binding recruits transcription factors (TFs) to the genome to regulate gene expression. Here, we perform high resolution mapping of CEBP proteins to determine how sequence dictates genomic occupancy. We demonstrate a fundamental difference between the sequence repertoire utilized by CEBPs in vivo versus the palindromic sequence preference reported by classical in vitro mode...

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Literature Corpus work: 9b196a8b-1259-56f2-bb43-b3dbfca0ffe1
DOI: 10.1101/262659

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