Article

BPabZIP, a new bZIP protein motif that promotes binding near, and displacement of, nucleosomes

2026-05-22

Abstract excerpt

Many transcription factors (TFs) bind only a subset of their canonical binding sites in mammalian cells. To identify differences between bound and unbound sites we examined Zta(N182S), a mutant of the Epstein Barr Virus (EBV)-encoded Zta bZIP protein that binds distinct DNA sequences that are not strongly bound by any known human or viral TF, reducing the effects of selective pressure on endogenous genomic binding...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 07a3f824-9bc2-5df9-8c87-936228b7fe1b
DOI: 10.64898/2026.05.20.725981

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

BPabZIP, a new bZIP protein motif that promotes binding near, and displacement of, nucleosomesDOI 10.64898/2026.05.20.725981Read

Epstein–Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expressionSemantic proximity Read

Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double-stranded DNA.Semantic proximity Read

Mutation of a single amino acid residue in the basic region of the Epstein-Barr virus (EBV) lytic cycle switch protein Zta (BZLF1) prevents reactivation of EBV from latency.Semantic proximity Read

ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanismSemantic proximity Read

Shared Nucleotide Flanks Confer Transcriptional Competency to bZip Core MotifsSemantic proximity Read

Shared nucleotide flanks confer transcriptional competency to bZip core motifs.Semantic proximity Read

Breaking TADs: How Alterations of Chromatin Domains Result in Disease.Semantic proximity Read

DNA flexibility regulates transcription factor binding to nucleosomesSemantic proximity Read

The Epstein-Barr Virus B-ZIP Protein Zta Recognizes Specific DNA Sequences Containing 5-Methylcytosine and 5-Hydroxymethylcytosine.Semantic proximity Read

Requirement for transcription factor IIA (TFIIA)-TFIID recruitment by an activator depends on promoter structure and template competition.Semantic proximity Read

Leukemia Risk Factor ARID5B Coordinates HDAC-Mediated Transcriptional RepressionSemantic proximity Read

Beyond accessibility: ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activationSemantic proximity Read