Article

MSICKB: A Curated Knowledgebase for Exploring Molecular Heterogeneity and Biomarker Discovery in Microsatellite Instability Cancers

2025-11-25

Abstract excerpt

<h4>Background</h4> Microsatellite instability (MSI) is a critical form of genomic instability and a key biomarker for predicting patient prognosis and response to immunotherapy in cancer. However, significant heterogeneity in clinical outcomes exists even among patients with MSI cancers of the same type, suggesting the presence of distinct molecular subtypes and the need for more personalized biomarkers. The sys...

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Literature Corpus work: 9afa9b93-d9b1-5eef-8791-232e52df557f
DOI: 10.1101/2025.11.22.689859

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