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Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal Cancer

1 Aug 2019

Abstract excerpt

Background: Colorectal cancer (CRC) is one of the most common cancers worldwide with high number of mortality every year. Microsatellite instability (MSI) is a considerable feature of CRC which affects prognosis and treatment. High level of MSI or MSI-high (MSI-H) colorectal cancer has better prognosis and immunotherapy response, while microsatellite stable (MSS) CRC has better response to 5-fluorouracil...

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PMID: 31450919
DOI: 10.31557/apjcp.2019.20.8.2445

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