Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic landscape of microsatellite instability in Chinese tumors: A comparison of Chinese and TCGA cohorts

14 May 2022

Abstract excerpt

Microsatellite instability (MSI) is an important biomarker for predicting the response to immunotherapy and prognosis that mainly results from a defective DNA mismatch repair (MMR) system and strongly correlates with high tumor mutation burden (TMB). Herein, we developed a novel method that integrates MSI score, MMR mutation status and TMB level to identify MSI status from next-generation sequencing (NGS) data....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Ferroptosis and cancer prognosis
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35567574
DOI: 10.1002/ijc.34119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic landscape of microsatellite instability in Chinese tumors: A comparison of Chinese and TCGA cohortsPMID 35567574Read ↗

Microsatellite instability in cancer: a novel landscape for diagnostic and therapeutic approach.Semantic proximity Read ↗

A molecular portrait of microsatellite instability across multiple cancersSemantic proximity Read ↗

Microsatellite instability: A 2024 update.Semantic proximity Read ↗

A molecular portrait of microsatellite instability across multiple cancers.Semantic proximity Read ↗

Microsatellite instability: a review of what the oncologist should knowSemantic proximity Read ↗

Large-Scale Cancer Genomic Analysis Reveals Significant Disparities between Microsatellite Instability and Tumor Mutational Burden.Semantic proximity Read ↗

MSICKB: A Curated Knowledgebase for Exploring Molecular Heterogeneity and Biomarker Discovery in Microsatellite Instability CancersSemantic proximity Read ↗

Microsatellite Instability: From the Implementation of the Detection to a Prognostic and Predictive Role in CancersSemantic proximity Read ↗

Comprehensive analysis of potential immunotherapy genomic biomarkers in 1000 Chinese patients with cancerSemantic proximity Read ↗

Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients.Semantic proximity Read ↗

Comprehensive analysis of potential immunotherapy genomic biomarkers in 1,000 Chinese patients with cancerSemantic proximity Read ↗

A Novel Approach for Characterizing Microsatellite Instability in Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.