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Article

Multi-omics characterization and validation of MSI-related molecular features across multiple malignancies.

Life sciences - 1 Apr 2021

Zheng Yuansheng, Huang Yiwei, Bi Guoshu, Du Yajing, Liang Jiaqi, Zhao Mengnan, Chen Zhencong, Zhan Cheng, Xi Junjie, Wang Qun

Abstract excerpt

HEADINGS AIMS: To establish a microsatellite instability (MSI) predictive model in pan-cancer and compare the multi-omics characterization of MSI-related molecular features. MATERIALS AND METHODS: We established a 15-gene signature for predicting MSI status and performed a systematic assessment of MSI-related molecular features including gene and miRNA expression, DNA methylation, and somatic mutation, in...

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Identifiers

PMID: 33516699
DOI: 10.1016/j.lfs.2021.119081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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