Article

Cancer-Associated Fibroblasts induce aggressive stem cell phenotype and chemoresistance in cervical tumoroid-fibroblast co-culture system via upregulating CK17 expression

2024-08-08

Abstract excerpt

<title>Abstract</title> <p>Cervical cancer is a serious health issue affecting women. Cancer development is the result of co-evolution between tumor cells and tumor stroma microenvironment, and Cancer Associated Fibroblasts (CAFs) is a significant part of tumor stroma and plays a big role in helping cancer cells grow, spread, and become aggressive. To investigate the biological function of CAFs in the progression...

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Literature Corpus work: 9ad55169-4538-529b-90a3-8db3ca2a7e40
DOI: 10.21203/rs.3.rs-4741458/v1

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