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Article

Cancer associated fibroblasts (CAFs) in tumor microenvironment

17 Dec 2009

Abstract excerpt

Cancer associated fibroblasts (CAFs) is one of the most crucial components of the tumor microenvironment which promotes the growth and invasion of cancer cells by various mechanisms. CAFs demonstrate a high degree of heterogeneity due to their various origins; however, many distinct morphological features and physiological functions of CAFs have been identified. It is becoming clear that the crosstalk between the...

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PMID: 20036813
DOI: 10.2741/3613

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