TGF ‐β1‐induced CK 17 enhances cancer stem cell‐like properties rather than EMT in promoting cervical cancer metastasis via the ERK 1/2‐ MZF 1 signaling pathway

Abstract excerpt

Tumor metastasis remains a major obstacle for improving overall cancer survival in cervical cancer (CC), which may be due to the existence of tumor microenvironment-related cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT). The mechanism underlying these processes needs to be further elucidated. Here, we report that TGF-β1, one of the key microenvironmental stimuli, can enhance CSC...

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