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Cancer-associated Fibroblasts: Origins, Heterogeneity and Functions in Tumor Microenvironment

2020-01-15

Abstract excerpt

Current therapeutic strategies targeting cancer cells within solid tumors have displayed limited success owing to the presence of non-cancer components referred to as the tumor stroma within the tumor microenvironment (TM). These stromal cells, extracellular matrix and blood vessels influence cancer cell response to therapy and play key roles in tumor relapse and resistance. Of the stromal cells present in the TM,...

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Literature Corpus work
6688cefc-a640-5aa3-b7e3-da24d94f8bb4
DOI
10.20944/preprints202001.0155.v1
Open publication

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