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Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinoma

2024-08-17

Abstract excerpt

<title>Abstract</title> <p>Understanding the intricate tumor microenvironment (TME) is crucial for elucidating the mechanisms underlying the progression of cervical squamous cell carcinoma (CSCC) and its response to anti-PD-1 therapy. In this study, we characterized 50,649 cells obtained from CSCC for single-cell RNA sequencing and integrated bulk sequencing data from The Cancer Genome Atlas (TCGA) and clinical s...

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Literature Corpus work
961a1bda-9f8a-5a65-b10a-09f69b37beaf
DOI
10.21203/rs.3.rs-4589423/v1
Open publication

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Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinomaDOI 10.21203/rs.3.rs-4589423/v1
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