Article

Imaging chromatin interactions at sub-kilobase resolution Via Tn5-FISH

2019-04-07

Abstract excerpt

<h4>ABSTRACT</h4> There is increasing interest in understanding how the three-dimensional organization of the genome is regulated. Different strategies have been employed to identify chromatin interactions genome wide. However, due to the current limitations in resolving genomic contacts, visualization and validation of these genomic loci with sub-kilobase resolution remain the bottleneck for many years. Here, we...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a53956e-9043-59d1-999e-5e65f1543d12
DOI: 10.1101/601690

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Imaging chromatin interactions at sub-kilobase resolution Via Tn5-FISHDOI 10.1101/601690Read

Detection of Allele-Specific 3D Chromatin Interactions Using High-Resolution In-Nucleus 4C-seq.Semantic proximity Read

Allele-level visualization of transcription and chromatin by high-throughput imaging.Semantic proximity Read

Dissecting the Contribution of Transposable Elements to Interphase Chromosome StructureSemantic proximity Read

Novel insights into chromosomal conformations in cancer.Semantic proximity Read

Identification of copy number variations and translocations in cancer cells from Hi-C dataSemantic proximity Read

Exploring the Dynamic 3D DNA Structures in Genomics: Towards New Diagnostic and Therapeutic FrontiersSemantic proximity Read

Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical ScreenSemantic proximity Read

Walking along chromosomes with super-resolution imaging, contact maps, and integrative modelingSemantic proximity Read

Ultrastructural details of mammalian chromosome architectureSemantic proximity Read

Dynamic interplay between structural variations and 3D chromosome organization in pancreatic cancerSemantic proximity Read

Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer.Semantic proximity Read

Whole genome optical mapping reveals multiple fusion events chained by large novel sequences in cancerSemantic proximity Read