Article

Dissecting the Contribution of Transposable Elements to Interphase Chromosome Structure

2024-10-27

Abstract excerpt

Transposable elements (TEs) occupy nearly half of the human genome and play diverse biological roles. Despite their abundance, the extent to which TEs contribute to three-dimensional (3D) genome structure remains unclear. To investigate this, we developed te_hic, a computational pipeline that integrates genomic data with chromatin interactions. Our analysis reveals that TE sequences are responsible for 3D genome s...

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Literature Corpus work: 4fa479d7-b6a9-512e-b234-14f2f31a0fd4
DOI: 10.1101/2024.10.25.620372

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