Article

Genomic Analyses of the Metastasis-derived LNCaP, VCaP, and PC3-AR Prostate Cancer Cell Lines

2021-06-26

Abstract excerpt

The lymph node metastasis-derived LNCaP, the bone metastasis-derived PC3 (skull), and VCaP (vertebral) cell lines are widely used preclinical models of human prostate cancer (CaP) and have been described in >19,000 publications. Here, we report on short-read whole-genome sequencing and genomic analyses of LNCaP, VCaP, and PC3 cells stably transduced with WT AR (PC3-AR). LNCaP cells are composed of multiple subpopu...

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Literature Corpus work: 9a09a8a1-bc55-5e9f-8f23-7bdcd7699440
DOI: 10.1101/2021.06.25.449904

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