Article

Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole Genome Sequencing

2021-08-10

Abstract excerpt

<h4>ABSTRACT</h4> A limited number of cell lines have fueled the majority of preclinical Prostate cancer (PCa) research. Despite tremendous effort in characterizing their molecular profiles, comprehensive whole genome sequencing with allelic phasing of somatic genome alterations has not been undertaken to date. Here, we utilized whole genome Linked-read sequencing to obtain haplotype information from the seven mo...

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Literature Corpus work: 67fd8acf-1742-5fb9-8dc1-f1d9854cda82
DOI: 10.1101/2021.08.09.455584

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