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Article

Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines.

G3 (Bethesda, Md.) - 7 Jun 2017

Seim Inge, Jeffery Penny L, Thomas Patrick B, Nelson Colleen C, Chopin Lisa K

Abstract excerpt

The bone metastasis-derived PC3 and the lymph node metastasis-derived LNCaP prostate cancer cell lines are widely studied, having been described in thousands of publications over the last four decades. Here, we report short-read whole-genome sequencing (WGS) and de novo assembly of PC3 (ATCC CRL-1435) and LNCaP (clone FGC; ATCC CRL-1740) at ∼70 × coverage. A known homozygous mutation in TP53 and homozygous loss...

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Identifiers

PMID: 28413162
DOI: 10.1534/g3.117.039909
PMCID: PMC5473753

Genes

CIC
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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